Less than 5% of all patients worldwide with CAH have 3-beta–hydroxysteroid dehydrogenase deficiency. In one study of 81 children with ambiguous genitalia, only 2 were found to have 3-beta–hydroxysteroid dehydrogenase deficiency. [10] The incidence is higher in some populations; 3-beta–hydroxysteroid dehydrogenase deficiency is relatively common in the Old Order Amish in North America associated with a HSD3B2 c.35G, a founder mutation. [11] Prognosis. A great deal of heterogeneity is observed with 3-beta–hydroxysteroid dehydrogenase deficiency. The most severely affected patients may have fatal salt-losing adrenal crises in infancy. By contrast, some patients with classic 3-beta–hydroxysteroid dehydrogenase deficiency do not have salt-losing crises; milder or late-onset variants have also been described in which patients do not present until later childhood or adolescence.
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If the hand opener is holding anything other than a premium hand, then they could well find themselves in trouble too. This is especially true when playing against a player who regularly folds to a 3 bet so be sure to 3 bet bluff more often if you have a weak hand. Even against a player who very rarely folds to 3 bets, this can lead to higher value hands while cutting out some potential bluffs. Another reason 3 and 4 betting is growing in popularity is to squeeze the most value possible out of a hand. This is especially true of the strongest hands such as AA/KK/QQ which you are more likely going to play anyway. Reddit and its partners use cookies and similar technologies to provide you with a better experience. What Top Poker Pros Already Know About 4-Betting. Mexico liga de expansion.
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